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In the batt­le to heal chro­nic wounds, the­re is an invi­si­ble enemy: . It’s a pri­ma­ry cau­se of chro­nic infec­tion [1], blo­cking the effec­ti­ve action of anti­bio­tic and anti­sep­tic agents [2]. And it’s pre­sent in at least 78% of chro­nic wounds [3]. But our bre­akthrough MORE THAN SILVER™ tech­no­lo­gy – sci­en­ti­fi­cal­ly deve­lo­ped to win the batt­le against – con­tains three com­pon­ents with the power to dis­rupt and des­troy bio­film: ionic sil­ver tog­e­ther with a sur­fac­tant and a metal chela­ting agent. Our dres­sing deli­vers supe­ri­or anti-bio­film per­for­mance com­pa­red to other sil­ver dres­sings [4,5]. We com­bi­ne MORE THAN SILVER™ with Hydro­fi­ber® tech­no­lo­gy, which works to absorb wound exu­da­te and dis­rup­ted EPS and bac­te­ria. This hel­ps to mana­ge wound mois­tu­re and sup­port healing [9].

Learn more about the MORE THAN SILVER™ tech­no­lo­gy and win the batt­le against bio­films in wounds.

[1] Bow­ler PG, Par­sons, D. Com­bat­ting wound and recal­ci­tran­ce with a novel anti- Hydro­fi­ber® wound dres­sing. Wound Medi­ci­ne 14 (2016) 6–11.
[2] Said J, Wal­ker, M, Par­sons D, Stap­le­ton P, Bee­zer AE, Gais­ford S. An in vitro test of the effi­cacy of an anti-bio­film wound dres­sing. Int J Phar­maceu­tics. 2014; 474: 177–181. DOI 10.1016/j ipharm.2014.08.034.
[3] Com­po­si­ti­on com­pri­sing anti­mi­cro­bi­al metal ions and a qua­terna­ry catio­nic sur­fac­tant WO12136968 Par­sons World app­li­ca­ti­on 11th Octo­ber 2012.
[4] Banin E., Bra­dy K.M. & Green­berg E.P. (2006). Chela­tor Indu­ced Disper­sal and Kil­ling of aeru­gi­no­sa Cells in Bio­film. Appl. Envi­ron. Micro­bi­ol. 72. 2064 2069.
[5] Chen X, Ste­wart PS, 2000. Bio­film remo­val cau­sed by che­mi­cal tre­at­ments. Wat. Res.
[6] 4229 4233. 34. Seth AK, Zhong A, Nguy­en KT, Hong SJ, Leung KP, Galia­no RD, Mus­toe TA. Impact of a novel, anto micro­bi­al dres­sing on in vivo, aeru­gi­no­sa wounds bio­film: quan­ti­ta­ti­ve com­pa­ra­ti­ve ana­ly­sis using a rab­bit ear model. Wound Repair Regen. 2014; 22: 712–719. DOI: 10.1111/wrr.12232.
[7] Hobot JA, Wal­ker M, New­man GN, Bow­ler PG. 2008. Effect of Hydro­fi­ber® wound dres­sings on bac­te­ri­al ultrast­ruc­tu­re. J Electr Micro; 57: 67–75.
[8] T. J. Beve­r­idge. W. S. Fyfe. Metal fixa­ti­on by bac­te­ri­al cell walls. Cana­di­an Jour­nal of Earth Sci­en­ces, 1985, 22(12): 1893–1898, https://doi.org/10.1139/e85-204.
[9] Par­sons, D, Mer­edith K, Row­lands VJ, Short D, Met­calf DG, Bow­ler PG. Enhan­ced Per­for­mance and Mode of Action of a Novel Anti­bio­film Hydro­fi­ber® Wound Dres­sing. Bio­med Res Int. 2016;2016:7616471.