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In the battle to heal chronic wounds, there is an invisi­ble enemy: biofilm. It’s a primary cause of chronic infec­tion [1], blocking the effec­tive action of antibio­tic and antisep­tic agents [2]. And it’s present in at least 78% of chronic wounds [3]. But our breakthrough MORE THAN SILVER™ techno­logy – scien­ti­fi­cally develo­ped to win the battle against biofilm – contains three compon­ents with the power to disrupt and destroy biofilm: ionic silver together with a surfac­tant and a metal chela­ting agent. Our dressing delivers superior anti-biofilm perfor­mance compa­red to other silver dressings [4,5]. We combine MORE THAN SILVER™ with Hydro­fi­ber® techno­logy, which works to absorb wound exudate and disrup­ted EPS and bacte­ria. This helps to manage wound moisture and support healing [9].

Learn more about the MORE THAN SILVER™ techno­logy and win the battle against biofilms in wounds.

[1] Bowler PG, Parsons, D. Combat­ting wound biofilm and recal­ci­trance with a novel anti-biofilm Hydro­fi­ber® wound dressing. Wound Medicine 14 (2016) 6–11.
[2] Said J, Walker, M, Parsons D, Staple­ton P, Beezer AE, Gaisford S. An in vitro test of the efficacy of an anti-biofilm wound dressing. Int J Pharmaceu­tics. 2014; 474: 177–181. DOI 10.1016/j ipharm.2014.08.034.
[3] Compo­si­tion compri­sing antimi­cro­bial metal ions and a quaternary catio­nic surfac­tant WO12136968 Parsons World patent appli­ca­tion 11th October 2012.
[4] Banin E., Brady K.M. & Green­berg E.P. (2006). Chela­tor Induced Disper­sal and Killing of Pseudo­mo­nas aerugi­nosa Cells in Biofilm. Appl. Environ. Micro­biol. 72. 2064 2069.
[5] Chen X, Stewart PS, 2000. Biofilm removal caused by chemi­cal treat­ments. Wat. Res.
[6] 4229 4233. 34. Seth AK, Zhong A, Nguyen KT, Hong SJ, Leung KP, Galiano RD, Mustoe TA. Impact of a novel, anto micro­bial dressing on in vivo, Pseudo­mo­nas aerugi­nosa wounds biofilm: quanti­ta­tive compa­ra­tive analy­sis using a rabbit ear model. Wound Repair Regen. 2014; 22: 712–719. DOI: 10.1111/wrr.12232.
[7] Hobot JA, Walker M, Newman GN, Bowler PG. 2008. Effect of Hydro­fi­ber® wound dressings on bacte­rial ultrast­ruc­ture. J Electr Micro; 57: 67–75.
[8] T. J. Bever­idge. W. S. Fyfe. Metal fixation by bacte­rial cell walls. Canadian Journal of Earth Scien­ces, 1985, 22(12): 1893–1898, https://doi.org/10.1139/e85-204.
[9] Parsons, D, Meredith K, Rowlands VJ, Short D, Metcalf DG, Bowler PG. Enhan­ced Perfor­mance and Mode of Action of a Novel Antibio­film Hydro­fi­ber® Wound Dressing. Biomed Res Int. 2016;2016:7616471.