In the battle to heal chronic wounds, there is an invisible enemy: biofilm. It’s a primary cause of chronic infection [1], blocking the effective action of antibiotic and antiseptic agents [2]. And it’s present in at least 78% of chronic wounds [3]. But our breakthrough MORE THAN SILVER™ technology – scientifically developed to win the battle against biofilm – contains three components with the power to disrupt and destroy biofilm: ionic silver together with a surfactant and a metal chelating agent. Our dressing delivers superior anti-biofilm performance compared to other silver dressings [4,5]. We combine MORE THAN SILVER™ with Hydrofiber® technology, which works to absorb wound exudate and disrupted EPS and bacteria. This helps to manage wound moisture and support healing [9].
Learn more about the MORE THAN SILVER™ technology and win the battle against biofilms in wounds.
[1] Bowler PG, Parsons, D. Combatting wound biofilm and recalcitrance with a novel anti-biofilm Hydrofiber® wound dressing. Wound Medicine 14 (2016) 6–11.
[2] Said J, Walker, M, Parsons D, Stapleton P, Beezer AE, Gaisford S. An in vitro test of the efficacy of an anti-biofilm wound dressing. Int J Pharmaceutics. 2014; 474: 177–181. DOI 10.1016/j ipharm.2014.08.034.
[3] Composition comprising antimicrobial metal ions and a quaternary cationic surfactant WO12136968 Parsons World patent application 11th October 2012.
[4] Banin E., Brady K.M. & Greenberg E.P. (2006). Chelator Induced Dispersal and Killing of Pseudomonas aeruginosa Cells in Biofilm. Appl. Environ. Microbiol. 72. 2064 2069.
[5] Chen X, Stewart PS, 2000. Biofilm removal caused by chemical treatments. Wat. Res.
[6] 4229 4233. 34. Seth AK, Zhong A, Nguyen KT, Hong SJ, Leung KP, Galiano RD, Mustoe TA. Impact of a novel, anto microbial dressing on in vivo, Pseudomonas aeruginosa wounds biofilm: quantitative comparative analysis using a rabbit ear model. Wound Repair Regen. 2014; 22: 712–719. DOI: 10.1111/wrr.12232.
[7] Hobot JA, Walker M, Newman GN, Bowler PG. 2008. Effect of Hydrofiber® wound dressings on bacterial ultrastructure. J Electr Micro; 57: 67–75.
[8] T. J. Beveridge. W. S. Fyfe. Metal fixation by bacterial cell walls. Canadian Journal of Earth Sciences, 1985, 22(12): 1893–1898, https://doi.org/10.1139/e85-204.
[9] Parsons, D, Meredith K, Rowlands VJ, Short D, Metcalf DG, Bowler PG. Enhanced Performance and Mode of Action of a Novel Antibiofilm Hydrofiber® Wound Dressing. Biomed Res Int. 2016;2016:7616471.